ULTRAGENYX PHARMACEUTICAL INC (RARE)

Sector: Health Care

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2026 Annual Meeting Analysis

ULTRAGENYX PHARMACEUTICAL INC · Meeting: May 14, 2026

Policy v1.2high confidenceView Filing ↗
For informational purposes only. This AI-generated analysis applies a published voting policy to publicly available proxy filings. It does not constitute investment advice, proxy voting advice, or a solicitation of any kind. AI analysis may be incomplete or inaccurate — always review the actual filing and make your own independent decision.

Directors FOR

0

Directors AGAINST

3

Say on Pay

AGAINST

Auditor

FOR

Director Elections

Election of Class I Directors

/3 AGAINST

Against Analysis

✗ AGAINST
Emil D. Kakkis, M.D., Ph.D.TSR underperformance trigger: RARE 3-year return -47.6% vs peer median +37.3%, gap of -84.9pp exceeds 20pp threshold for negative absolute TSR5-year TSR confirms sustained underperformance: -81.9% vs peer median +45.0%, gap of -126.9pp far exceeds thresholdDirector since 2010 — full tenure overlap with underperformance period

Dr. Kakkis has served as CEO and director since the company's founding in 2010, giving him full accountability for the stock's severe 3-year decline of nearly 48%, which trails the company's own peer group by about 85 percentage points — well above the 20-point trigger threshold; the 5-year record is even worse at -82%, confirming this is sustained, not temporary, underperformance.

✗ AGAINST
Shehnaaz Suliman, M.D.TSR underperformance trigger: RARE 3-year return -47.6% vs peer median +37.3%, gap of -84.9pp exceeds 20pp threshold for negative absolute TSR5-year TSR confirms sustained underperformance: gap of -126.9pp far exceeds thresholdDirector since 2019 — full 3-year tenure overlap with underperformance period

Dr. Suliman joined the board in 2019, meaning she has been a director throughout the entire 3-year underperformance window; with the stock down nearly 48% while peers gained about 37%, the gap of roughly 85 percentage points far exceeds the 20-point trigger, and the 5-year record provides no mitigation as it is similarly poor.

✗ AGAINST
Daniel G. WelchTSR underperformance trigger: RARE 3-year return -47.6% vs peer median +37.3%, gap of -84.9pp exceeds 20pp threshold for negative absolute TSR5-year TSR confirms sustained underperformance: gap of -126.9pp far exceeds thresholdDirector since 2015 and Independent Chairman — full tenure overlap with underperformance period, heightened accountability as board chair

Mr. Welch has served as a director since 2015 and as Independent Chairman, giving him direct responsibility for board oversight during the full underperformance period; with RARE trailing its peer group by about 85 percentage points over three years and by nearly 127 percentage points over five years, both the 3-year trigger and 5-year confirmation point firmly to a vote against.

For Analysis

All three Class I nominees are subject to the TSR underperformance trigger: Ultragenyx's stock has fallen roughly 48% over three years while its disclosed peer group gained about 37%, a gap of 85 percentage points that far exceeds the 20-point threshold for companies with negative absolute returns. The 5-year record is worse still, providing no mitigation. All three directors have served throughout the underperformance period and receive AGAINST votes.

Say on Pay

✗ AGAINST

CEO

Emil D. Kakkis, M.D., Ph.D.

Total Comp

$11,405,535

Prior Support

68%%

Prior say-on-pay support below 70% threshold (68% in 2025) with incomplete remediationPay-for-performance misalignment: variable/incentive pay above benchmark while stock dramatically underperforms peersCEO total compensation of $11.4M while stock declined ~48% over 3 years and underperformed XBI — SPDR S&P Biotech ETF by over 109 percentage points

Ultragenyx received only 68% support on last year's say-on-pay vote — below the 70% threshold that triggers a No vote unless meaningful changes are made; while the company has taken some positive steps (downward discretion on bonuses, increased performance-based award percentages, longer vesting periods), the core misalignment between pay and shareholder outcomes remains severe. The CEO received over $11.4 million in total compensation for a year in which the stock fell roughly 48% and trailed the XBI — SPDR S&P Biotech ETF by more than 109 percentage points over three years, representing one of the worst records among the company's own disclosed peers. The incremental governance improvements made in response to last year's vote do not sufficiently address the fundamental disconnect between executive pay levels and the shareholder experience over a sustained multi-year period.

Auditor Ratification

✓ FOR

Auditor

Ernst & Young LLP

Tenure

N/A

Audit Fees

$2,610,000

Non-Audit Fees

$108,000

Ernst & Young's non-audit fees (tax compliance and advisory work) totaled $108,000 against audit fees of $2,610,000, a ratio of about 4% — well below the 50% threshold that would raise independence concerns; EY is a Big 4 firm appropriate for a company of Ultragenyx's size; while the proxy states EY has audited the company 'since inception,' a specific tenure year is not disclosed, so the tenure trigger cannot be confirmed and does not fire under policy.

Overall Assessment

All three Class I director nominees receive AGAINST votes due to severe and sustained stock price underperformance — Ultragenyx has trailed its own disclosed peer group by approximately 85 percentage points over three years and nearly 127 percentage points over five years, with both the CEO/founder and independent directors bearing full accountability. The say-on-pay vote also receives an AGAINST determination driven by the combination of below-70% prior-year support and a fundamental misalignment between executive pay levels and the shareholder experience reflected in the stock's dramatic underperformance versus the XBI benchmark; the auditor ratification passes cleanly with a non-audit fee ratio of only about 4%.

Filing date: March 27, 2026·Policy v1.2·high confidence

Compensation Peer Group

19 companies disclosed in 2026 proxy filing

ACADACADIA Pharmaceuticals Inc.
ADMAADMA Biologics, Inc.
ALKSAlkermes plc
FOLDAmicus Therapeutics
APLSApellis Pharmaceuticals, Inc.
AXSMAxsome Therapeutics, Inc.
BCRXBioCryst Pharmaceuticals, Inc.
BPMCBlueprint Medicines Corporation
BBIOBridgeBio Pharma, Inc.
CORTCorcept Therapeutics Inc.
DNLIDenali Therapeutics Inc.
HALOHalozyme Therapeutics
IONSIonis Pharmaceuticals, Inc.
JAZZJazz Pharmaceuticals plc
MDGLMadrigal Pharmaceuticals Inc.
MIRMMirum Pharmaceutical, Inc.
PTCTPTC Therapeutics, Inc.
SRPTSarepta Therapeutics, Inc.
VCELVericel Corporation