KYMERA THERAPEUTICS INC (KYMR)

Sector: Health Care

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2026 Annual Meeting Analysis

KYMERA THERAPEUTICS INC · Meeting: June 24, 2026

Policy v1.2high confidenceView Filing ↗
For informational purposes only. This AI-generated analysis applies a published voting policy to publicly available proxy filings. It does not constitute investment advice, proxy voting advice, or a solicitation of any kind. AI analysis may be incomplete or inaccurate — always review the actual filing and make your own independent decision.

Directors FOR

4

Directors AGAINST

0

Say on Pay

FOR

Auditor

FOR

Director Elections

Election of Four Class III Directors

4 FOR
✓ FOR
Bruce Booth, D.Phil.

Director since 2015 with strong relevant life sciences and venture capital experience; KYMR's 3-year return of +147.4% outperforms the peer group median by +80.7 percentage points, well above the 50pp threshold required to trigger a withhold vote for strong-positive TSR companies, and no other policy flags apply.

✓ FOR
Nello Mainolfi, Ph.D.

CEO and director since 2019 with deep scientific and operational expertise as the company's founder; the TSR trigger does not apply given KYMR outperforms the peer group by +80.7 percentage points over three years, and the pay program is evaluated separately under Say on Pay.

✓ FOR
John Maraganore, Ph.D.

Director since January 2022 with extensive biotech CEO experience at Alnylam and multiple public board roles; the TSR trigger does not apply, all meetings were attended at or above the 75% threshold, and no other policy flags are present.

✓ FOR
Elena Ridloff, CFA

Director since March 2021 with strong financial expertise as designated Audit Committee financial expert and CFO experience at multiple public life sciences companies; the TSR trigger does not apply and no other policy flags are present.

All four Class III director nominees receive a FOR vote. KYMR's 3-year total shareholder return of +147.4% outperforms the XBI — SPDR S&P Biotech ETF by +89.5 percentage points and the company's disclosed compensation peer group median by +80.7 percentage points, comfortably clearing the 65pp threshold required to trigger a withhold vote for companies with strong positive absolute returns. All directors attended 75% or more of meetings in 2025, none are overboarded under policy thresholds, no family relationships exist among directors or executives, all independent directors serve on appropriate committees, and the board includes a designated audit financial expert. The slate is well-qualified with relevant biotech, financial, and scientific expertise.

Say on Pay

✓ FOR

CEO

Nello Mainolfi, Ph.D.

Total Comp

$8,545,609

Prior Support

88%%

CEO total compensation of approximately $8.5 million is reasonable for the founder-CEO of a $6.7 billion clinical-stage biotech company and is well within expected benchmarks for the role, title, and market cap band. The pay structure is strongly performance-oriented — the proxy states that 92% of CEO pay and 86% of other named executive officer pay on average is 'at-risk,' with a meaningful mix of time-based stock options, performance-based stock options, and performance stock units tied to specific clinical milestones, satisfying the policy requirement that at least 50-60% of senior executive pay be variable. Pay-for-performance alignment is strong: KYMR's stock returned +147.4% over three years versus the XBI — SPDR S&P Biotech ETF's +57.9%, and the board awarded a 125% of target bonus payout reflecting genuine 2025 operational achievements including positive Phase 1b data for KT-621, initiation of Phase 2b studies, a new Gilead partnership, and $980.7 million raised. The company has a clawback policy in place, prior Say on Pay support was 88% (well above the 70% threshold), and there are no material governance concerns with the compensation program structure.

Auditor Ratification

✓ FOR

Auditor

Ernst & Young LLP

Tenure

8 yrs

Audit Fees

$1,377,253

Non-Audit Fees

$40,000

Ernst & Young LLP has served as Kymera's auditor since 2018 (approximately 8 years), well below the 25-year tenure threshold that would trigger a concern. Non-audit fees of $40,000 (tax work) represent only about 2.9% of audit fees of $1,377,253, far below the 50% ratio that would raise independence concerns. EY is a Big 4 firm fully appropriate for a company of KYMR's size and complexity, and there are no disclosed financial restatements.

Overall Assessment

Kymera Therapeutics' 2026 annual meeting ballot contains three proposals, all of which warrant a FOR vote. The company has delivered outstanding shareholder returns over the past three years (+147.4%), significantly outperforming both the XBI — SPDR S&P Biotech ETF and its disclosed compensation peer group, the director slate is well-qualified with no overboarding or attendance concerns, the auditor relationship is clean with minimal non-audit fees, and the executive compensation program is predominantly performance-based and aligned with the strong operational progress the company achieved in 2025.

Filing date: April 29, 2026·Policy v1.2·high confidence

Compensation Peer Group

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