Michael Lee has served as a director since July 2018. Mr. Lee has served as Co-Founder and Portfolio Manager at Redmile Group, LLC ( Redmile ) since 2007. Prior to Redmile, Mr. Lee worked as a biotechnology investor at Steeple Capital, and as an analyst at Welch Capital Partners and Prudential Equity Group. Mr. Lee previously served on the board of directors of IGM Biosciences, Inc. (formerly Nasdaq: IGMS, acquired by Concentra Biosciences, LLC in August 2025) from July 2019 to August 2025 and Shattuck Labs, Inc. (Nasdaq: STTK) from June 2020 to August 2025. Mr. Lee holds a B.S. in Molecular and Cellular Biology from the University of Arizona. The Board of Directors has determined that Mr. Lee s extensive business and leadership experience in the biotechnology industry qualifies him to serve as a member of our Board of Directors.