John Maraganore, Ph.D., has served on our board of directors since November 2021. He is the CEO and Principal of JMM Innovations, LLC and the Co-CEO of Corsera Health, a biotechnology company. He was previously the founding CEO and a director of Alnylam Pharmaceuticals ("Alnylam") from 2002 to 2021, where he built and led the company from early platform research on RNA interference through global approval and commercialization of the first three RNAi medicines including ONPATTRO , GIVLAARI , and OXLUMO . Prior to Alnylam, Dr. Maraganore served as an officer and a member of the management team for Millennium Pharmaceuticals, Inc. ("Millennium"), most recently as senior vice president, strategic product development where he was responsible for the company s product franchises in oncology, and cardiovascular, inflammatory, and metabolic diseases. Before Millennium, he served as director of molecular biology and director of market and business development at Biogen, Inc. ("Biogen"). At Biogen, Dr. Maraganore invented and led the discovery and development of ANGIOMAX (bivalirudin) for injection, formerly HIRULOG and currently marketed by The Medicines Company. Prior to Biogen, Dr. Maraganore was a scientist at ZymoGenetics, Inc., and the Upjohn Company. Dr. Maraganore received his M.S. and Ph.D. in biochemistry and molecular biology at the University of Chicago. He is a member of the board of directors of Kymera Therapeutics, Takeda Pharmaceuticals, and Rapport Therapeutics, as well as a number of private companies. He is also a member of the board of the Biotechnology Innovation Organization (BIO), where he was Chair from 2017-2019. In addition, he serves in advisory roles for a number of investment and banking firms, including Arch Ventures, Atlas Ventures, Blackstone Life Sciences, Jefferies Financial Services, and RTW Investments. We believe that Dr. Maraganore's significant experience in executive roles in the biotechnology industry qualifies him to serve on our board of directors.