Jonathan Poole has served as a director of the Company since March 2026. Since March 2020, Mr. Poole has served as Senior Vice President, Finance at Vertex Pharmaceuticals, Inc., where he leads the global finance team supporting corporate, commercial, research and development, manufacturing and other functions, overseeing significant business growth and the execution and integration of various acquisitions. Previously, from July 2018 through March 2020, Mr. Poole served as a director of Codiak Biosciences, Inc. and as the chair of Codiak s audit committee. From March 2018 to March 2020, Mr. Poole also served as Chief Financial Officer of Evelo Biosciences, Inc., a biotechnology company developing orally delivered product candidates designed to act on the small intestinal axis, and from April 2014 to March 2018, Mr. Poole was Chief Financial Officer of Genocea Biosciences, Inc., a biotechnology company developing neoantigen cancer vaccines. Mr. Poole received a B.Sc. in Biological Sciences from Durham University in the United Kingdom and an M.B.A. from London Business School. The NCG Committee believes that Mr. Poole is qualified to serve as a member of our board of directors based on his extensive executive leadership experience, financial expertise and deep knowledge of the biotechnology industry.